Menopause transition is associated with changes in body composition including an increase in fat mass, a decrease in lean mass, and an increase in abdominal adiposity.
Semaglutide, also known as Ozempic, is a drug that can help with weight loss when used in conjunction with diet and exercise. It works by mimicking glucagon-like peptide 1 (GLP-1), a hormone released in the gut after eating that interacts with the brain to suppress appetite.
Used with Hormone Replacement Therapy, Semaglutide may offer a good solution to achieve rapid weight loss around the Menopasue transition, pending reliable evidence.
In this symposium Prof Bassel Wattar and Prof Vikram Talaulikar discuss the findings of a retrospective observational study from the USA that evaluated the benefits of using Semaglutide with and without HRT in women in the menopause.
Link to the YouTube video:
Link to full article: https://journals.lww.com/menopausejournal/fulltext/2024/04000/weight_loss_response_to_semaglutide_in.4.aspx
